ea0099ep1303 | Late Breaking | ECE2024
Palioura Eleni
, Herolidi Eleni
, Kalogeris Nikolaos
, Dermentzoglou Alexandros
, Katsafyloudi Maria
, Konidaris Alexandros
, Tsekes Georgios
, Chini Maria
, Vryonidou Andromahi
Introduction: HIV infection has been associated with bone loss and increased frequency of bone fractures. The main pathogenetic mechanisms involve the direct effect of the virus and the HIV-induced inflammatory cytokines on bone metabolism, the effect of antiretroviral therapy (cART) per se and the frequently coexisting nutritional disorders and hypogonadism, further accelerating bone loss. Bisphosphonates remain the first-line treatment for these patients. Limited da...